喹唑啉胺盐酸盐的稳定多晶形物及其制备方法和医药用途

Stable polymorph of N-(3-ethynylphenylamino)-6,7-bis (2-methoxyethoxy)-4-quinazolinamine hydrochloride, method of production and pharmaceutical uses thereof

  • Inventors:
  • Assignees: Osi药物公司
  • Publication Date: November 28, 2007
  • Publication Number: CN-100351241-C

Abstract

本发明涉及被指定为B型多晶形物的N-(3-乙炔基苯基)-6,7-二(2-甲氧基乙氧基)-4-喹唑啉胺盐酸盐的稳定结晶型,其基本上纯的结晶型的制备方法,及其应用。本发明还涉及含有N-(3-乙炔基苯基)-6,7-二(2-甲氧基乙氧基)-4-喹唑啉胺盐酸盐的稳定B型多晶形物以及该化合物的其它形式的组合物,本发明还涉及通过给药该化合物治疗过度增殖性疾病如癌症的方法。

Claims

Description

Topics

Download Full PDF Version (Non-Commercial Use)

Patent Citations (0)

    Publication numberPublication dateAssigneeTitle

NO-Patent Citations (0)

    Title

Cited By (0)

    Publication numberPublication dateAssigneeTitle